PropertyValue
?:abstract
  • The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout China and many other countries around the world The antivirals are important measures to this epidemic;however, there is no drug approved for against coronavirus yet With the continuously rising number of confirmed/suspected cases of COVID-19, it is urgent to obtain antiviral drugs for the clinical treatment In response to this situation, drug repurposing strategy becomes one of the best approaches for anti-SARS-CoV-2 drug discovery By retrieving the clinical trials registered in Chinese Clinical Trial Registry and ClinicalTrials gov, a total of 14 chemical drugs were registered for COVID-19 In this review, we summarize and analyze the 14 drugs\' indications, targets, and research basis related to the activities against viral infections, esp coronavirus infections We are making efforts to understand the evidence basis of these drugs for the treatment of SARS-CoV-2 infection applied by various research and clinical institutions in response to this COVID-19 outbreak, and also providing clues for quick response to possible epidemic in future and reasonable expansion of the indications of drugs
is ?:annotates of
?:creator
?:journal
  • Yaoxue_Xuebao
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Analysis of chemical drugs applied for clinical trial for the treatment of COVID-19
?:type
?:who_covidence_id
  • #918559
?:year
  • 2020

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