PropertyValue
?:abstract
  • Aim: The authors studied the role of soluble ST2 (sST2) in COVID-19 and its relationship with inflammatory status and disease severity. Materials & methods: Serum levels of sST2 and interleukin (IL)-33, C-reactive protein (CRP), serum amyloid protein (SAA), IL-6 and procalcitonin (PCT), and T lymphocyte subsets from 80 subjects diagnosed with COVID-19 including 36 mild, 41 severe and three asymptomatic cases were tested. Results: Serum sST2 levels were significantly increased in COVID-19 patients, which were positively correlated with CRP, but negatively correlated with CD4+ and CD8+ T lymphocyte counts. Serum sST2 levels in nonsurviving severe cases were persistently high during disease progression. Conclusion: Serum sST2 level test is helpful for reflecting inflammatory status and illness severity of COVID-19.
is ?:annotates of
?:creator
?:doi
?:doi
  • 10.2217/bmm-2020-0410
?:journal
  • Biomarkers_in_medicine
?:license
  • unk
?:pmid
?:pmid
  • 33336592
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • Medline
?:title
  • Serum-soluble ST2 as a novel biomarker reflecting inflammatory status and illness severity in patients with COVID-19.
?:type
?:year
  • 2020-12-01

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