PropertyValue
?:abstract
  • Angiotensin-converting enzyme 2 (ACE 2) is the entry receptor for the novel coronavirus SARS-CoV-2, the aetiological agent of COVID-19. At the same time, ACE 2 expression decreases during COVID-19. Two seemingly contradictory relationships between the expression of ACE 2 and COVID-19 have been reported. Increased level of expression of ACE 2 may be a risk factor for the development of COVID-19 infection, while reduced ACE 2 expression during COVID-19 leads to acute respiratory distress syndrome. This article provides a comprehensive overview of available scientific knowledge about the role of ACE 2 in the pathogenesis of COVID-19, which is available up to current day. Also, it discusses unknown factors that we will have to reveal in order to understand the whole role of ACE 2 in the pathogenesis of COVID-19.
?:creator
?:doi
?:doi
  • 10.1080/17843286.2020.1786324
?:journal
  • Acta_clinica_Belgica
?:license
  • unk
?:pmid
?:pmid
  • 32597377
?:publication_isRelatedTo_Disease
?:source
  • Medline
?:title
  • The role of angiotensin-converting enzyme 2 in the pathogenesis of COVID-19: the villain or the hero?
?:type
?:year
  • 2020-06-27

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