PropertyValue
?:abstract
  • INTRODUCTION: In order to minimise the risk of breast cancer patients for COVID-19 infection related morbidity and mortality prioritisation of care has utmost importance since the onset of the pandemic. However, COVID-19 related risk in patients undergoing breast cancer surgery has not been studied yet. We evaluated the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland region. METHODS: A prospective cohort study of patients having breast cancer surgery was carried out in a geographical region during the first eight weeks of the hospital lockdown and outcomes were compared to the regional cancer registry data of pre-COVID-19 patients of the same units (n=1415). RESULTS: 188 operations were carried out in 179 patients. Tumour size was significantly larger in patients undergoing surgery during hospital lockdown than before (cT3-4: 16.8% vs. 7.4%; p<0.001; pT2 – pT4: 45.5% vs. 35.6%; p=0.002). ER negative and HER-2 positive rate was significantly higher during lockdown (ER negative: 41.3% vs. 17%, p<0.001; HER-2 positive: 23.4% vs. 14.8%; p=0.004). While breast conservation rate was lower during lockdown (58.6% vs. 65%; p<0.001), level II oncoplastic conservation was significantly higher in order to reduce mastectomy rate (22.8% vs. 5.6%; p<0.001). No immediate reconstruction was offered during lockdown. 51.2% had co-morbidity, and 7.8% developed postoperative complications in lockdown. There was no peri-operative COVID-19 infection related morbidity or mortality. CONCLUSION: breast cancer can be safely provided during COVID-19 pandemic in selected patients.
is ?:annotates of
?:creator
?:doi
  • 10.1016/j.breast.2020.11.015
?:doi
?:journal
  • Breast
?:license
  • no-cc
?:pdf_json_files
  • document_parses/pdf_json/c392d52ae0de63d456343d335252f468b2a66f70.json
?:pmc_json_files
  • document_parses/pmc_json/PMC7687359.xml.json
?:pmcid
?:pmid
?:pmid
  • 33285400.0
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:sha_id
?:source
  • Elsevier; Medline; PMC
?:title
  • A prospective cohort study of the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland
?:type
?:year
  • 2020-11-25

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