PropertyValue
?:abstract
  • Background: SARS-CoV-2 causes COVID19 disease where there are no suitable drugs available. Objective: The objective of the work is to repurpose the drugs prescribed for SARS-CoV as the drugs for the control of SARS-CoV-2. Methods: In this work, we have used homology searches and docking methods for understanding the mechanism of the drugs prescribed for the control of SARS-CoV on SARS-CoV-2. Results: In our analysis, we found that the drugs Benzyl (2-Oxopropyl)carbamate, 2-[(2,4-Dichloro-5-methyl phenyl)sulfonyl]-1,3-dinitro-5-(trifluoromethyl)benzene, S-[5-(Trifluoromethyl)-4H-1,2,4-triazol-3-YL] 5-(phenylethynyl)furan-2-carbothioate, 4-(Dimethylamino)benzoic acid, which are capable of inhibition of the activity of 3CL Proand prevent the progression of SARS-CoV. Conclusion: In this letter, we describe the findings of the protein ligand interactions between 3CL Proof SARS-CoV, SARS-CoV-2 with Benzyl (2-oxopropyl) carbamate.
is ?:annotates of
?:creator
?:journal
  • Lett._Drug._Des._Discov.
?:license
  • unk
?:publication_isRelatedTo_Disease
is ?:relation_isRelatedTo_publication of
?:source
  • WHO
?:title
  • Drug re-purposing from SARS-CoV led the identification of potential candidate drug target and alternate drug molecules against SARS-CoV-2
?:type
?:who_covidence_id
  • #818743
?:year
  • 2020

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