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  • Molecular assay reagents intended to identify mutations in the MAX interacting protein 1 (MXI1) gene, located at chromosome 10q24-25, which encodes for a protein that is a transcriptional repressor, thought to negatively regulate Myc function. This gene is a potential tumor suppressor. Mutations at this locus have been identified in patients with neurofibrosarcoma and susceptibility to prostate cancer.
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